ProgrammeWednesday 4th June : 13h30-14h30: Bus transportation from Grenoble train station to Domaine de l’Escandille, Autrans 14h30-15h Welcoming – Registration, poster hanging 15h-15h15 Congress opening by the local organizing committee and president of SFA Session 1: Organ specificity of endothelial cells-Angiocrine factors- Chairpersons Isabelle Brunet et Thomas Mathivet 15h15-15h45: Keynote speaker: Shahin Rafii (Cornell University, USA)-Chairman 15h45-16h15: Invited speaker: Benoit Vanhollebeke (Brussels Univ, Belgium): Single-cell control mechanism of brain angiogenesis and blood-brain barrier formation. 16h15-17h15: 4 selected short talks: 16h15-16h30: Braud Gaétan, PARCC, Paris: Controlling blood-CNS barrier integrity in health and disease 16h30-16h45: Kemps Hannelore, KU Leuven: Endothelial Prdm16 limits infarct growth by maintaining cerebrovascular function during ischemic stroke. 16h45-17h00: Dehais Vianney, CIRB Paris: Unraveling the Role of Peripheral Nerve Vasculature in Oxaliplatin-Induced Neuropathy. 17h00-17h15: Vialet Léa, Biosanté CEA Grenoble: Deciphering hepatic and cardiac BMP10 functions in vascular homeostasis using tissue-specific Bmp10-KO mice model. 17h15-17h45 coffee break Session 2: Vascular resilience and plasticity- chairpersons Lucas Treps and Nicolas Ricard 17h45 -18h15: Invited speaker: Stephanie Dimmeler (Franckfurt, Germany): Ageing effects on the vascular niche 18h15-18h45: 2 selected short talks: 18h15-18h30: Christophe Guignabert, Université Paris-Saclay, Paris : Hypoxia Impairs Pulmonary Endothelial Cell Adaptation to Shear Stress. 18h30-18h45: Boulestreau Romain, INSERMU1034 Bordeaux : Wnt Signaling in Perivascular Fibroblasts: a key regulator of CNS vasculature stabilization. Poster session: 18h45-19h45 19h45: Dinner and conference party Thrusday 5th June : Session 3: Immune modulation of vascular function- Chairpersons Vanessa Petit and Florent Morfoisse 8h30-9h00: Invited speaker: Laurent Yvan-Charvet (Nice, France): Glutamine Metabolism in Arterial Wall Remodeling. 9h00-9h45: 3 selected short talks: 9h00-9h15: Labrosse Mathilde, Biosanté CEA Grenoble: Immunomodulatory Role of BMP9 and BMP10 via The Attenuation of IL-6/JAK/STAT Signalling in Endothelial Cells. 9h15-9h30: Treps Lucas, CRCI2NA, Nantes: In vitro models to mimic tumor endothelial cell-mediated immune cell reprograming in lung adenocarcinoma. 9h30-9h45: Ghersi Joey, University of Montreal, Canada: The embryonic endothelial cells control hematopoietic stem cell heterogeneity. 9h45-10h15: Coffee Break Session 4: Mechanobiology of the endothelium- Chairpersons Cécile Duplàa and Nicolas Baeyens 10h15-10h45: Keynote speaker: Martin Schwartz (Yale, USA): Endothelial shear stress sensing and vascular morphogenesis. 10h45-11h15: Invited speaker: Hans Van Oosterwyck (Leuven, Belgium): Quantifying endothelial cell force exertion
11h15-11h45: 3 selected short talks: 11h15-11h30: Priyadarshani Jyotsana, KU Leuven, Leuven: A novel 3DTFM-integrated vessel-on-a-chip platform capturing the mechanobiology of CCM2-silenced vessels. 11h30-11h45: Barakat Abdul, Ecole Polytechnique, Paris: Biophysics of Angiogenic Sprouting: A Nematic Perspective. 11h45-12h00: Alonso Florian, Inserm U1026, Bordeaux: Mutation of the extracellular matrix protein fibrillin-1 disrupts endothelial cell quiescence. Poster session: 12h00-13h00/ General assembly SFA 13h-14h: Lunch Session 5: Metabolic and epigenetic control of vascular functions- Chairpersons Sébastien Dumas and Shahin Rafii 14h00-14h30: Invited speaker: Michael Potente (Berlin, Germany): Deconvoluting complex vascular phenotypes using induced proximity approaches. 14h30-15h15: 3 selected short talks: 14h30-14h45: Cantelmo Anna Rita, Institut Pasteur, Lille: Functional and metabolic role of AIF/CHCHD4 pathway in endothelial cells. 14h45-15h00: Devetter Florian, INSERM U1313, Poitiers: Putative role of miR-126-3p in modulating angiogenesis signaling in a model of ischemia-reperfusion injury. 15h00-15h15: Domingues Alison, UMR1144, Paris: Impact of Aging-Related Comorbidities on the Neurovascular Unit and Stroke Recovery. 15h15-19h00: Free time for outdoor activities 19h00-20h00 Dinner Session 6: Vascularization of organs on chip - Engineering of cardiovascular tissue- Chairpersons Marie Ouarné and Eva Faurobert 20h00-20h30: Invited speaker: Laurent Muller (Paris, France): Microfluidic platform for angiogenesis
and cell sheet-based organ on chip.
20h30-21h15: 3 selected short talks: 20h30-20h45: Simon-Yarza Teresa, LVTS, Paris: Development of a 3D pre-vascularized structured hydrogel membrane for outer blood-retina modelling and therapy for choroidal dystrophies. 20h45-21h00: Leroy Alice, LiMMS, Lille: Blood vessels-on-chip for studying the effects of anti-cancer therapies on the vascular barrier. 21h00-21h15: Tubbs Emily, CEA Grenoble: A microfluidic platform integrating functional vascularized organoids-on-chip. Friday 6th of June Session 7: Vascular malformations and pathological angiogenesis- Chairpersons Christophe Guignabert and Sabine Bailly 8h00-8h30 : Invited Speaker : Guillaume Canaud (Paris, France): From mechanisms to targeted therapies in vascular malformations. 8h30-9h00 : Invited Speaker : Giorgo Seano (Paris, France): Vascular changes drive resistance to therapy in glioblastoma. 9h00-10h15 : 5 selected short talks: 9h00-9h15: Rida Yasmin, Biosanté CEA, Grenoble: Endothelial ALK1 is Critical for Maintaining Vascular Integrity and Liver Function in Adulthood. 9h15-9h30: Baeyens Nicolas, ULB, Bruxelles: Reversal of cerebrovascular anomalies in a zebrafish model of Vein of Galen aneurysm. 9h30-9h45: Lopes Mélanie, CEA Grenoble: Development of a Vascularized Human Langerhans Islet Model on a Microfluidic Chip: Towards Personalized Medicine for Type 1 Diabetes. 9h45-10h00: Boulday Gwénola, ICM, Paris: VSMC phenotype switching: An early mechanism involved in Moyamoya angiopathy. 10h00-10h15: Aziz Abdel-Ilah, Université de Reims, Reims: CD160 as a Key Modulator of Angiogenesis Through Its Interaction with LRP1. 10h15-10h45: coffee break Session 8: Lymphangiogenesis- chairpersons Claire Bouvard and Mathilde Poulet 10h45-11h15: Invited Speaker : Amélie Sabine (Lausanne, Switzerland): Dynamic regulation of endothelial barrier function: storage or protection? 11h15-11h45: Invited Speaker : Barbara Garmy-Susini (Toulouse, France): Innovative therapeutic strategies for lymphatic diseases. 11h45-12h00: 1 selected short talk 11h45-12h00: Morfoisse Florent, I2MC, Toulouse: A lymphatic vessel-on-chip platform reveals mechanically-induced inflammation and barrier dysfunction. 12h: Closing and Awards 12h15-13h30: Lunch Box 13h30: Departure from Escandille (Bus transportation to Grenoble train station)
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